Arthralgia
 |
16% | 96% |
Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954 |
| Blood Rapid Antibody Test
|
99.7% | 99.9% |
from whole blood Study: AIDS. 2006 Aug 1;20(12):1655-1660. PMID 16868447 |
| Diarrhea
|
8% | 98% |
Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954 |
| Emesis
|
13% | 97% |
Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954 |
| Fatigue
|
22% | 92% |
Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954 |
| Fever
|
33% | 90% |
Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954 |
| Genital Ulcer
|
8% | 99% |
Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954 |
| genital wart
|
2% | 99% |
Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954 |
| Headache
|
18% | 91% |
Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954 |
| HIV RNA PCR
|
100% | 97% |
All false positives had levels < 2000 copies/ml. Study: Ann Intern Med 2001 Jan 2;134(1):25-9. PMID 11187417 |
| nausea
|
10% | 97% |
Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954 |
| Night Sweats
|
12% | 96% |
Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954 |
| Oral Rapid Antibody Test
|
99.9% | 96.9% |
aka "OraSure" or "OraQuick" . Another study found sens = 99.1% and spec = 99.6%. Study: sens: JAMA 1997 Jan 15;277(3):254-8. PMID 9005276
spec: Ann Intern Med. 2008 Aug 5;149(3):153-60. PMID 18678842
alternative: AIDS. 2006 Aug 1;20(12):1655-1660. PMID 16868447 |
| Oral ulcer
|
13% | 96% |
Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954 |
| p24 Antigen
|
89% | 100% |
Study: Ann Intern Med 2001 Jan 2;134(1):25-9. PMID 11187417 |
| Rash
|
6% | 96% |
Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954 |
| Salivary gland enlargement, bilateral
|
No accuracy specified. |
Study: no study specified. |
| Swollen Lymph Nodes
|
11% | 98% |
Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954 |
| Thrush
|
No accuracy specified. |
Study: no study specified. |
| Weight loss
|
21% | 96% |
Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954 |
| Western Blot
|
99.3% | 99.7% |
'window period' of seronegativity is approximately 3-6 weeks in newest-generation assays. p24 antigen should be sensitive in this timeframe. Study: CDC Survey, cited in UpToDate
http://www.utdol.com/online/content/topic.do?topicKey=hiv_infe/5102 |