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Good Positive and Negative Likelihood Ratios

Good Positive Likelihood Ratio

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Human Immunodeficiency Virus: Likelihood Ratios

Introduction: None written.

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Tags: Infection Tag this Diagnosis.

Prevalence

Population / CalculatorPrevalence Comments / Study / Link
1000 2%
More, Edit...

The likelihood ratios of findings for Human Immunodeficiency Virus are listed below. See the left navigation bar to change the display.

Good Positive and Negative Likelihood Ratios

Finding +LR-LR Comments, Study
Blood Rapid Antibody Test Edit 9970

from whole blood

Study: AIDS. 2006 Aug 1;20(12):1655-1660. PMID 16868447

Western Blot Edit 3310

'window period' of seronegativity is approximately 3-6 weeks in newest-generation assays. p24 antigen should be sensitive in this timeframe.

Study: CDC Survey, cited in UpToDate

http://www.utdol.com/online/content/topic.do?topicKey=hiv_infe/5102

HIV RNA PCR Edit 33.30

All false positives had levels < 2000 copies/ml.

Study: Ann Intern Med 2001 Jan 2;134(1):25-9. PMID 11187417

Oral Rapid Antibody Test Edit 32.20

aka "OraSure" or "OraQuick" . Another study found sens = 99.1% and spec = 99.6%.

Study: sens: JAMA 1997 Jan 15;277(3):254-8. PMID 9005276

spec: Ann Intern Med. 2008 Aug 5;149(3):153-60. PMID 18678842

alternative: AIDS. 2006 Aug 1;20(12):1655-1660. PMID 16868447

p24 Antigen Edit inf0.1

Study: Ann Intern Med 2001 Jan 2;134(1):25-9. PMID 11187417

Good Positive Likelihood Ratio

Finding +LR-LR Comments, Study
Genital Ulcer Edit 80.9

Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954

Swollen Lymph Nodes Edit 5.50.9

Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954

Weight loss Edit 5.30.8

Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954

Emesis Edit 4.30.9

Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954

Diarrhea Edit 40.9

Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954

Arthralgia Edit 40.9

Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954

Fever Edit 3.30.7

Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954

Oral ulcer Edit 3.30.9

Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954

nausea Edit 3.30.9

Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954

Night Sweats Edit 30.9

Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954

Fatigue Edit 2.80.8

Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954

Headache Edit 20.9

Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954

genital wart Edit 21

Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954

Poorly Diagnostic Findings

Finding +LR-LR Comments, Study
Rash Edit 1.51

Study: Wood, E., Kerr, T., Rowell, G., Montaner, J. S. G., Phillips, P., Korthuis, P. T., & Simel, D. L. (2014). Does This Adult Patient Have Early HIV Infection? JAMA, 312(3), 278. doi:10.1001/jama.2014.5954

Findings With Unspecified Accuracy

Finding +LR-LR Comments, Study
Thrush Edit No accuracy specified.

Study: no study specified.

Salivary gland enlargement, bilateral Edit No accuracy specified.

Study: no study specified.