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Specific Findings

Sensitive Findings

Diabetic Ketoacidosis: Sensitivity and Specificity

Introduction: Acidemia from ketone production in a state of (at least functional) hypoinsulinemia and hyperglycemia. Much more common in type 1 Diabetes Mellitus.

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Tags: Endocrine Metabolic Tag this Diagnosis.

Prevalence

Population / CalculatorPrevalence Comments / Study / Link
Hyperglycemia and suspicious symptoms 14% patients presenting to the ED; glucose > 200 and either known diabetic + DKA-like symptoms or no diabetes diagnosis

Ann Emerg Med. 1999 Sep;34(3):342-6. PMID: 10459090

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The sensitivity and specificity of findings for Diabetic Ketoacidosis are listed below. See the left navigation bar to change the display.

Sensitive and Specific Findings

Finding SensitivitySpecificity Comments, Study
Anion Gap Edit 92%85%

Study: Ann Emerg Med. 1999 Sep;34(3):342-6. PMID: 10459090

Specific Findings

Finding SensitivitySpecificity Comments, Study
Abnormal Serum Bicarbonate Edit 84%99%

HCO3 < 15 mEq/l

Study: Ann Emerg Med. 1999 Sep;34(3):342-6. PMID: 10459090

Sensitive Findings

Finding SensitivitySpecificity Comments, Study
Urine Ketones Edit 99%69%

urine dipstick

Study: Ann Emerg Med. 1999 Sep;34(3):342-6. PMID: 10459090